The 10th Mediterranean Conference on Information Systems will be held in Cyprus on 4-6 September 2016. MCIS 2016 invites academics and researchers, from all over the world but also especially from the Mediterranean region, to reflect on innovative research in information systems, from the point of view of a rapidly changing world. The Mediterranean Conference on Information Systems (MCIS) aims to encourage and inspire innovative and informative IS research that is relevant to the social, economic and cultural particularities of the Mediterranean region, raise the visibility of IS-related research practice, education and policy carried out in the Med. Region and bring together researchers, educators, policy makers and practitioners originating from, or working in the region, thus engaging junior and more experienced members of the Mediterranean IS community in a creative dialogue.